非アルコール性脂肪性肝疾患のベッドサイド超音波診断-SIFSOF

The thyroid is a butterfly-shaped gland that sits low on the front of the neck. The thyroid lies below Adam’s apple, along the front of the windpipe. It has two side lobes, connected by a bridge (isthmus) in the middle. The thyroid secretes several hormones, collectively called thyroid hormones. The main hormone is thyroxine, also called T4. Thyroid hormones act throughout the body, influencing metabolism, growth and development, and body temperature. During infancy and childhood, adequate thyroid hormone is crucial for brain development. Clinical trials have established a link between hypothyroidism and nonalcaholic fatty liver disease.

脂肪症または脂肪肝, is a common result of moderate to severe insult to Hepatocytes which are major parenchymal cells in the liver which play a pivotal roles in metabolism, detoxification, and protein synthesis. Hepatocytes also activate innate immunity against invading microorganisms by secreting innate immunity proteins.

甲状腺機能が低下すると、代謝が遅くなり、甲状腺刺激ホルモン（TSH）レベルが上昇します。これはまた、体内の脂肪の蓄積につながり、非アルコール性脂肪性肝疾患（NAFLD）を発症するリスクを高めます。

過去20年間で、非アルコール性脂肪肝疾患は世界で最も一般的な肝疾患の25つになり、子供を含む世界人口のほぼXNUMX％を占めています。

Hepatic steatosis is diagnosed by ultrasound after exclusion of infectious and metabolic disorders. While ultrasound diagnosis and fasting serum samples are taken for determination of thyroid function (TSH, FT4, and FT3), along with alanine aminotransferase (ALT), lipid profile, glucose, insulin, and insulin resistance.

Ultrasound is a non-invasive, widely available, and accurate tool in the detection of Non-alcoholic fatty liver disease (NAFLD). Ultrasound should be used as the first-line diagnostic test in patients with abnormal liver enzymes when other causes are excluded. Clinical risk factors, when used with ultrasound findings, have high accuracy in identifying NAFLD patients. There is an an algorithm for chronic abnormal liver enzymes that illustrates the use of ultrasound in reducing the need for liver biopsy in the diagnosis of NAFLD. Although Clinicians should be aware of the known limitations of ultrasound, including the inability to grade or stage fibrosis in NAFLD patients.

上記の超音波アプリケーションでは、次のXNUMXつの超音波トランスデューサーをお勧めします。

カラードップラーワイヤレス凸型超音波スキャナー3.5-5MHz、SIFULTRAS-5.21. This device is best suitable for detection of non alcaholic fatty liver disease. It allows you to visualize liver function and make diagnoses quickly and confidently.
リニアワイヤレス超音波スキャナーシフルトラ-5.34 – equipped with a high resolution 7.5 MHz transducer this device is recommended for measuring thyroid size and morphology with the subjects sitting and their necks slightly extended. Thyroid volume is defined as enlarged according to the reference values for age, gender, and body surface area.

この手順は、適格な内分泌専門医によって実行されます

参照：甲状腺機能低下症と非アルコール性脂肪肝疾患：病態生理学的関連と治療上の意味
 太りすぎおよび肥満の子供における脂肪肝および甲状腺機能検査